SLE is an autoimmune disease capable of causing severe tissue damage in many organs. The cause of SLE is unknown, but recent research has identified infection-fighting proteins called interferons (or IFNs) which are made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells. IFNs allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors.
Increased severity of lupus and African-American women focus of Lupus Foundation of Minnesota-funded research at University of Minnesota
Researchers who seek new biomarkers for human diseases may have many goals. In the field of lupus research, we would like to find biomarkers that could make the disease easier to diagnose, improve the management of disease activity, predict when a flare is likely to occur, and help physicians decide which medications to use (or avoid) in a particular patient.
Thanks to advances in genomic and proteomic technologies over the past 10 years, lupus researchers have been successful in ...