My name is Ami Yamamoto, and I have the great opportunity of being one of the Lupus Foundation of Minnesota’s Student Summer Fellows for 2013. This summer, I am studying under Erik Peterson, M.D., in the Department of Rheumatic and Autoimmune Diseases at the University of Minnesota–Twin Cities.
As I will write about in more detail in a later post, my project is to contribute to research on the gene PTPN22 which Dr. Peterson and his team thinks to be a “risk” gene for Systemic Lupus Erythematosus (SLE). The first step for the project is gathering approximately 150 SLE patient participants and genotyping their DNA (extracted from a small tube of blood they donated for the cause) to determine whether they have the “LypR” variant or the “LypW” variant. We hypothesize that patients with the “LypW” variant (who we call “carriers”) are at higher risk for SLE and that SLE patients with LypW variant PTPN22 have ...Continue Reading →