Over the past two weeks, I have performed pilot experiments to finalize the design of my final project. One of these pilots compared an infected wild type model with an uninfected one; wild type means that the model has not been genetically modified in any way.
A day after infection, I examined spleen for the presence of certain dendritic cell variants. Dendritic cells are one of many types of white blood cells, and some of their subsets are found in greater numbers during infection. Therefore, I expected to find more of these dendritic cells after lymphocytic choriomeningitis virus (LCMV) infection. Dendritic cells are an essential part of the immune system, as they detect foreign bodies, such as pathogens, and present the pathogen’s antigens to T cells. Antigens are the surface proteins on cells that act as a recognition system. Your body has a set of antigens that are unique, so your immune cells can recognize you and find foreign cells. The ...Continue Reading →